The Grady Trauma Project
The Grady Trauma Project (GTP) is a large-scale study of the impacts of stress- and trauma-related risk factors for posttraumatic stress disorder (PTSD) and related behavioral and physical health comorbidities in a high risk, highly trauma exposed urban population of Black Americans in Atlanta, GA, USA.
This interdisciplinary team of investigators is led by Co-Directors Abigail Lott, PhD, ABPP (Director of Treatment Research and Education), Vasiliki Michopoulos, PhD (Director of Translational Neuroscience), and Jennifer Stevens, PhD (Director of Human Neuroscience).
The GTP leverages translational techniques, such as neuroimaging, physiology and psychophysiology, to study the underlying biology of adverse health outcomes related to trauma exposure and PTSD. Over the last 15 years, the GTP has conducted trauma interviews on over 12,000 participants recruited from medical clinic waiting rooms at Grady Memorial Hospital in Atlanta, GA.
Data from GTP indicate high rates of trauma exposure, with >90% reporting at least one trauma, and 46% meeting lifetime diagnostic criteria for PTSD.
Current GTP studies are trying to 1) understand the mechanisms by which women are more at risk than men for PTSD and other stress- and trauma-related adverse health outcomes and co-morbidities (e.g. reproductive dysfunction, cardiovascular and metabolic disease, immune dysfunction, infectious disease, cancer and aging), 2) identify new neurobiological treatment targets following acute trauma exposure, and 3) develop culturally informed evidence-based, accessible interventions for PTSD other stress- and trauma-related adverse health outcomes with the long term goal of reducing health inequities and improving health outcomes in Black communities.
Please look further at our various projects:
The combined effects of HIV and estrogen insufficiency induced pro-inflammatory state on end-organ health in women aging with HIV infection: A project of the Emory SCORE – Project PI Vasiliki Michopoulos, PhD MScR